Nanokinetics says nanoemulsions boosted Δ8-THC absorption 19 times in preclinical study

Nanokinetics, a division of Industrial Sonomechanics, says a preclinical pharmacokinetic study found its liquid and powdered Δ8-THC nanoemulsions delivered up to 19 times greater absorption than an MCT-oil solution. The research, now in press at AAPS PharmSciTech, points to faster and more consistent oral delivery for infused products and dry-format applications.

Why it matters: - The study targets a core problem in oral infused products: lipophilic ingredients do not dissolve well in water, which can reduce absorption and make onset uneven. - Higher absorption can improve dose efficiency, since more of the active ingredient reaches systemic circulation. - Powdered nano-formulations could expand use cases into tablets, sachets, gummies and capsules.

What happened: - Nanokinetics completed a preclinical pharmacokinetic study comparing two orally administered Δ8-THC nanoemulsions, one liquid and one powdered, against a conventional Δ8-THC solution in MCT oil. - The pharmacokinetic comparison is in press at AAPS PharmSciTech. - The company says the nanoemulsion formulations outperformed the oil-based control across the study.

The details: - The headline result reached 19X greater absorption versus the MCT-oil control. - Both the liquid and powdered nanoemulsion formats retained the performance advantage. - Nanokinetics says its technology reformulates bioactives as nanometer-scale oil droplets in water or in a dry water-soluble binder. - The company says the approach can make oral delivery faster-acting, more bioavailable and more stable. - Nanokinetics develops and produces water-soluble liquid and powdered nano-formulations for the beverage, food and nutraceutical industries. - The company uses a proprietary high-intensity ultrasonic process. - Nanokinetics says it can formulate kratom, kava, hemp, mushroom extracts, berberine, Coenzyme Q10 and piperine into water-compatible ingredients. - Services include custom formulation development, feasibility testing, contract manufacturing and tolling at small and large scale.

Between the lines: - The split between liquid and powdered formats matters because it suggests the same delivery gains may work across both beverage-style and dry-product applications. - The result also reflects a broader industry push to improve consistency in products built around ingredients that are hard to absorb orally. - The claim is preclinical, so it supports formulation potential rather than consumer-level outcomes.

What's next: - The study will move through publication in AAPS PharmSciTech. - Nanokinetics is positioning the result as support for broader use of its nano-formulation platform in food, beverage and nutraceutical products. - Brands and manufacturers can use the platform for custom development and contract production if they want to test dry or liquid delivery formats.

The bottom line: - Nanokinetics is betting that nanoemulsion delivery can make oral cannabinoids and other botanical actives more efficient, more predictable and easier to formulate across product types.